- Patients with cervical esophageal carcinoma
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Patients with T1N0 disease, T4 disease, and proximal esophageal cancers (15-24 cm)
Prior systemic chemotherapy for esophageal cancer (note that prior chemotherapy for a different cancer is allowable)
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Prior radiation therapy for esophageal cancer or prior chest radiotherapy
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Prior anthracycline or taxane
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Evidence of tracheoesophageal fistula or invasion into the trachea or major bronchi
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Prior invasive malignancy (except non-melanomatous skin cancer), unless disease free for a minimum of 2 years (e.g., carcinoma in situ of the breast, oral cavity, or cervix are permissible)
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Medical contraindications to esophagectomy
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