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EXActDNA-003 / NSABP B-64: Breast Cancer Clinical Validation Study to Predict Recurrence of High-Risk Early Breast Cancer Treated With Neoadjuvant Therapy Using a Bespoke Circulating Tumor DNA Assay to Detect Molecular Residual Disease

Keywords: Oncology (Adult);Breast Cancer; ctDNA; Neoplasms by Site; Neoplasms; Breast…
Study Type: OBSERVATIONAL   |  Region: California - Northern

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A RANDOMIZED PHASE III STUDY OF BENDAMUSTINE PLUS RITUXIMAB VERSUS IBRUTINIB PLUS RITUXIMAB VERSUS IBRUTINIB ALONE IN UNTREATED OLDER PATIENTS (= 65 YEARS OF AGE) WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)

Keywords: Oncology (Adult);Hematology;
Study Type: INTERVENTIONAL   |  Region: California - Northern

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A Phase 2 Randomized Study of Irinotecan/Temozolomide/Dinutuximab With or Without Eflornithine (DFMO) in Children With Relapsed, Refractory or Progressive Neuroblastoma

Keywords: Neuroblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal…
Study Type: INTERVENTIONAL   |  Region: California - Northern

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A Phase 3 Open-Label, Randomized, Controlled, Global Study of Telisotuzumab Vedotin (ABBV-399) Versus Docetaxel in Subjects with Previously Treated c-Met Overexpressing, EGFR Wildtype, Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer

Keywords: Oncology (Adult);
Study Type: INTERVENTIONAL   |  Region: Hawaii

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Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)

Keywords: Carcinoma; Neoplasms; Liver Neoplasms; Hepatoblastoma; Neoplasms; Glandular and…
Study Type: INTERVENTIONAL   |  Region: California - Northern

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A Phase 3 Open-label, Randomised Study of Datopotamab Deruxtecan (DatoDXd) With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Who Have Residual Invasive Disease in the Breast and/or Axillary Lymph Nodes at Surgical Resection Following Neoadjuvant Systemic Therapy (TROPION-Breast03)

Keywords: Breast Cancer; TNBC; Triple-negative; Adjuvant; Datopotamab Deruxtecan;…
Study Type: INTERVENTIONAL   |  Region: California - Northern

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Randomized Phase III Trial of mFOLFIRINOX vs. FOLFOX With Nivolumab for First-Line Treatment of Metastatic HER2- Gastroesophageal Adenocarcinoma

Keywords: Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic…
Study Type: INTERVENTIONAL   |  Region: California - Northern

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Stopping Tyrosine Kinase Inhibitors (TKI) to Assess Treatment-Free Remission (TFR) in Pediatric Chronic Myeloid Leukemia - Chronic Phase (CML-CP)

Keywords: Leukemia; Leukemia; Myeloid; Leukemia; Myelogenous; Chronic; BCR-ABL Positive;…
Study Type: INTERVENTIONAL   |  Region: California - Northern

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A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine Versus Selumetinib (NSC# 748727) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) Not Associated With BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)

Keywords: Oncology (Pediatrics); Oncology…
Study Type: INTERVENTIONAL   |  Region: California - Northern

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Randomized Trial of Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia (AML)

Keywords: Oncology (Adult);Hematology;
Study Type: INTERVENTIONAL   |  Region: California - Northern

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