- No prior neurotoxic chemotherapy
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No pre-existing clinical or pre-clinical peripheral neuropathy from any cause.
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No history of seizure disorder,
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No history of narrow-angle glaucoma.
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No symptoms of or history of schizophrenia, bipolar disease, suicidal thoughts and/or a major depression.
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No serious eating disorder such as bulimia or anorexia.
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No known diagnosis of ethanol (ETOH) addiction/dependence within the past 10 years.
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Not pregnant and not nursing, because this study involves an investigational agent whose genotoxic, mutagenic and teratogenic effects on the developing fetus and newborn are unknown. Therefore, for women of childbearing potential, a negative pregnancy test done =< 7 days prior to registration is required
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