Current Inclusion Criteria, as of 6/28/2024

Ischemic stroke within the prior 7 days.

NIH Stroke Scale Score =1 at the time of enrollment

Previous Inclusion Criteria, prior to 6/28/2024:

Ischemic stroke or TIA with ABCD =4, within prior 14 days.

pre-event inability to perform all of own basic ADLs

unable to obtain informed consent from subject or legally authorized representative

incarcerated

known pregnancy

current mechanical ventilation (can enroll later if this resolves) or tracheostomy

current use of positive airway pressure, or use within one month prior to stroke

anatomical or dermatologic anomaly that makes use of CPAP interface unfeasible

severe bullous lung disease

history of prior spontaneous pneumothorax or current pneumothorax

hypotension requiring current treatment with pressors (can enroll later if this resolves)

other specific medical circumstances that conceivably, in the opinion of the site PI, could render the patient at risk of harm from use of CPAP

massive epistaxis or previous history of massive epistaxis

cranial surgery or head trauma within the past 6 months, with known or possible CSF leak or pneumocephalus

recent hemicraniectomy or suboccipital craniectomy (i.e. those whose bone has not yet been replaced), or any other recent bone removal procedure for relief of intracranial pressure

current receipt of oxygen supplementation >4 liters per minute

current contact, droplet, respiratory/airborne precautions

• Brain Diseases

• Cardiovascular Diseases

• Central Nervous System Diseases

• Cerebrovascular Disorders

• Dyssomnias

• Intrinsic

• Ischemic Stroke

• Nervous System Diseases

• Neurology/Neurological Disorders

• Obstructive

• Respiration Disorders

• Respiratory

• Respiratory Tract Diseases

• Signs and Symptoms

• Sleep Apnea

• Sleep Apnea Syndromes

• Sleep Disorders

• Sleep Wake Disorders

• Stroke

• Vascular Diseases

• Apnea

• University of Michigan